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PRF, or platelet-rich fibrin, is the next generation treatment of platelet concentrate. PRF is a fibrin matrix comprised of platelet cytokines, growth factors and cells used to help promote skin rejuvenation, hair growth and wound healing.
Fibrin is a biological scaffold that forms in response to an injury anywhere in the body. Platelets circulating in the blood will bind to a scaffold of fibrin. When platelets bind to the fibrin scaffold, they become activated and release growth factors, which start the wound healing process by creating new skin cells, collagen and blood vessels. By injecting PRF into an area on the face or scalp, a controlled inflammatory response is created, which kick starts new cell growth and collagen production.
Results can vary from person to person. For hair loss treatments, usually 3-4 monthly consecutive treatments are needed, which is then followed by quarterly treatments to maintain the results. After a year, the treatment frequency can be reduced, based on the specific requirements of the patient.
If you are experiencing hair loss, you’re basically a good candidate for PRF hair restoration However, the growth factors, white blood cells, stem cells, and platelets in the PRF work best when awakening dormant hair follicles. These hair follicles are still healthy and capable of growing hair, but they are spending more and more time in dormant phase. That’s why PRF hair restoration works best when the patient notices early hair loss.
PRF works well for both men and women, especially those in the early stages of hair loss. It also is effective for women with traction alopecia, hair thinning caused by hairstyles that pulled the hair to an extreme degree and inhibited hair growth. It is also a good procedure for people whose hair is thinning but who don’t want to resort to taking medications regularly.
Any anti-inflammatory medications and certain supplements will need to be stopped, as they can lead to bleeding and bruising.
Otherwise, it’s a good idea to drink plenty of fluids and hydrate fully for the three days prior to your PRF session.
There isn’t really any recovery. You may take an over-the-counter pain medication if you feel any soreness, but you can shower and wash your hair immediately. Don’t use ice packs on your scalp, as the cold can inhibit the PRF activity. Your scalp may be a little pink or red across the treatment areas for several hours after your session. We usually recommend holding off one to two days with typical hair maintenance, such as blow drying, coloring, curling, etc.